Wanting pulls away from liking

Incentive-sensitization holds that repeated use sensitizes the wanting system (incentive salience) while the liking system (hedonic pleasure) habituates with tolerance. Raise the sensitization rate and watch craving climb as enjoyment falls — the widening gap is why an addicted person can want a drug intensely while liking it less and less.

Sensitization rate of wanting (s)0.35
0.000.250.500.751.00strength (0–1)use number (n)wantingliking
With sensitization rate s = 0.35, by use 12 wanting has risen to 1.00 while liking has fallen to 0.19. Wanting overtakes liking at use 2: past this point the drug is craved more than it is enjoyed, the dissociation that defines the theory.

From reward to relief: the allostatic cycle

Each use delivers a fixed acute pleasure A = 100, but triggers an opposing b-process that grows toward a ceiling 60: bn = 60[1 − (1 − g)n]. Net pleasure is Pn = A − bn; the withdrawal nadir between uses is |Wn| = bn. Where they cross, relief of withdrawal overtakes reward as the motive to use.

b-process growth rate (g)0.30
0255075100magnitude (units)use number (n)n = 5.02net pleasurewithdrawal
With g = 0.30, net pleasure runs 82.0 → 69.4 → 60.6 over the first three uses while withdrawal deepens 18.0 → 30.6 → 39.4. Reward and relief cross at use 5.02 — from there on the drug is taken more to escape withdrawal than to feel pleasure, the shift from positive to negative reinforcement. (This is the article's worked example.)

Seeking that survives punishment

As addiction progresses, control of drug-seeking devolves from a goal-directed system toward a stimulus-bound compulsive one, and sensitivity to punishment falls with it. Move the behaviour along that transition and apply a punishment: early on it suppresses seeking almost entirely, but at the compulsive end seeking persists regardless — the experimental hallmark of compulsion.

Stage of the transition to compulsionhabitual, early
0.00.51.0seeking rateno punishment1.00under punishment0.17
At the habitual, early stage, punishment leaves seeking at 0.17 of its unpunished rate — a partial suppression — the behaviour is sliding out of punishment's reach as control becomes habitual.