Route sets the time course

The same nominal dose produces two opposite plasma-THC profiles. Smoking delivers a tall, early peak within minutes; swallowing delivers a lower, delayed one after about an hour. Drag the dose to scale both curves.

Nominal THC dose10 mg
1h2h3htime after doseplasma THCsmokedoral

Smoked peaks at about 5 min and roughly 5.2× higher than the oral peak at about 86 min. The tall early spike is the felt onset that makes moment-to-moment control — and self-titration — possible; the oral route's slow, unfelt rise is what invites overshoot.

Self-titration and overshoot

Because a smoker feels each puff within a minute or two, they can stop at a target level — ideal titration. But a lag between inhaling and feeling the effect, or an unfamiliar potency, pushes intake past the target before the signal arrives. Adjust the feedback lag and the per-puff dose.

Feedback laginstant
Dose per puff (unfamiliar potency raises this)1.0×
targetpuff number

With instant feedback and familiar material the smoker stops at 7 puffs, essentially at target — the controlled dosing the smoked route allows.

The impairment window vs. the detection window

Meaningful driving impairment is concentrated in a short, early window after smoking, while THC stays detectable for far longer. Raise the dose to see the impairment window (shaded) grow — but stay far shorter than the period of mere presence.

Nominal THC dose10 mg
2h4h6h8himpairment thresholddetection floortime after smoking

Meaningful impairment lasts about 18 min, but THC stays detectable for about 52 min — roughly 2.9× longer. A blood level drawn hours later tracks mere presence, not how impaired the driver was, which is why per-se blood-THC limits rest on a concentration–impairment link the smoked route's pharmacokinetics do not support.